Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses

In colorectal cancers, the tumor microenvironment plays a key role in prognosis and therapy efficacy. Patient-derived tumor organoids (PDTO) show enormous potential for preclinical testing; however, cultured tumor cells lose important characteristics, including the consensus molecular subtypes (CMS)...

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Detalles Bibliográficos
Autores principales: Farin, Henner F., Mosa, Mohammed H., Ndreshkjana, Benardina, Grebbin, Britta M., Ritter, Birgit, Menche, Constantin, Kennel, Kilian B., Ziegler, Paul K., Szabó, Lili, Bollrath, Julia, Rieder, Dietmar, Michels, Birgitta E., Kress, Alena, Bozlar, Müge, Darvishi, Tahmineh, Stier, Sara, Kur, Ivan-Maximilano, Bankov, Katrin, Kesselring, Rebecca, Fichtner-Feigl, Stefan, Brüne, Bernhard, Goetze, Thorsten O., Al-Batran, Salah-Eddin, Brandts, Christian H., Bechstein, Wolf O., Wild, Peter J., Weigert, Andreas, Müller, Susanne, Knapp, Stefan, Trajanoski, Zlatko, Greten, Florian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551667/
https://www.ncbi.nlm.nih.gov/pubmed/37489084
http://dx.doi.org/10.1158/2159-8290.CD-23-0050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551667/
https://www.ncbi.nlm.nih.gov/pubmed/37489084
http://dx.doi.org/10.1158/2159-8290.CD-23-0050

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