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Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability
Centromere (CEN) identity is specified epigenetically by specialized nucleosomes containing evolutionarily conserved CEN-specific histone H3 variant CENP-A (Cse4 in Saccharomyces cerevisiae, CENP-A in humans), which is essential for faithful chromosome segregation. However, the epigenetic mechanisms...
Autores principales: | Mishra, Prashant K., Au, Wei-Chun, Castineira, Pedro G., Ali, Nazrin, Stanton, John, Boeckmann, Lars, Takahashi, Yoshimitsu, Costanzo, Michael, Boone, Charles, Bloom, Kerry S., Thorpe, Peter H., Basrai, Munira A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551700/ https://www.ncbi.nlm.nih.gov/pubmed/37436802 http://dx.doi.org/10.1091/mbc.E23-03-0108 |
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