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Effects of rifampin coadministration on the pharmacokinetics of digoxin: a real-world data approach

Digoxin, a cardiac glycoside, is commonly prescribed to treat heart failure and atrial fibrillation. Because digoxin acts as a substrate of P-glycoprotein (P-gp), its blood concentration may be reduced by P-gp inducers such as rifampin. To assess the real-world implications of this drug-drug interac...

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Detalles Bibliográficos
Autores principales: Oh, JungJin, Kim, Byungwook, Lee, SeungHwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551748/
https://www.ncbi.nlm.nih.gov/pubmed/37810625
http://dx.doi.org/10.12793/tcp.2023.31.e13