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p21 promotes gemcitabine tolerance in A549 cells by inhibiting DNA damage and altering the cell cycle

Gemcitabine is one of the most widely used chemotherapy drugs for advanced malignant tumors, including non-small cell lung cancer. However, the clinical efficacy of gemcitabine is limited due to drug resistance. The aim of the present study was to investigate the role of p21 in gemcitabine-resistant...

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Detalles Bibliográficos
Autores principales: Fu, Tian, Ma, Xuan, Du, Shen-Lin, Ke, Zhi-Yin, Wang, Xue-Chun, Yin, Hai-Han, Wang, Wen-Xuan, Liu, Yong-Jun, Liang, Ai-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551858/
https://www.ncbi.nlm.nih.gov/pubmed/37809050
http://dx.doi.org/10.3892/ol.2023.14059