Single-Cell Lipidomics Using Analytical Flow LC-MS Characterizes the Response to Chemotherapy in Cultured Pancreatic Cancer Cells

[Image: see text] In this work, we demonstrate the development and first application of nanocapillary sampling followed by analytical flow liquid chromatography–mass spectrometry for single-cell lipidomics. Around 260 lipids were tentatively identified in a single cell, demonstrating remarkable sens...

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Detalles Bibliográficos
Autores principales: Saunders, Kyle D. G., von Gerichten, Johanna, Lewis, Holly-May, Gupta, Priyanka, Spick, Matt, Costa, Catia, Velliou, Eirini, Bailey, Melanie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551860/
https://www.ncbi.nlm.nih.gov/pubmed/37725657
http://dx.doi.org/10.1021/acs.analchem.3c02854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551860/
https://www.ncbi.nlm.nih.gov/pubmed/37725657
http://dx.doi.org/10.1021/acs.analchem.3c02854

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