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RediScore: Prospective validation of a pipeline for homologous recombination deficiency analysis

Tumors harboring homologous recombination deficiency (HRD) are considered optimal candidates for poly(ADP-ribose) polymerase 1 (PARP) inhibitor treatment. Such deficiency can be detected by analyzing breast cancer type (BRCA)1/2 gene mutations, as well as mutations in other genes of the homologous r...

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Detalles Bibliográficos
Autores principales: Tsantikidi, Aikaterini, Papazisis, Konstantinos, Floros, Theofanis, Gazouli, Maria, Papadopoulou, Eirini, Tsaousis, Georgios, Nasioulas, Georgios, Mester, Andra, Milan, Kubelac Paul, Gozman, Bogdan, Afrasanie, Vlad, Stanculeanu, Dana Lucia, Trifanescu, Oana, Pescaru, Florentina, Militaru, Claudia, Papadimitriou, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551864/
https://www.ncbi.nlm.nih.gov/pubmed/37809048
http://dx.doi.org/10.3892/ol.2023.14060