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15-keto-PGE(2) alleviates nonalcoholic steatohepatitis through its covalent modification of NF-κB factors
15-keto-PGE(2) is one of the eicosanoids with anti-inflammatory properties. In this study, we demonstrated that 15-keto-PGE(2) post-translationally modified the nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) subunits p105/p50 and p65 at Cys59 and Cys120 sites, respectively, hence...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551900/ https://www.ncbi.nlm.nih.gov/pubmed/37810249 http://dx.doi.org/10.1016/j.isci.2023.107997 |