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15-keto-PGE(2) alleviates nonalcoholic steatohepatitis through its covalent modification of NF-κB factors

15-keto-PGE(2) is one of the eicosanoids with anti-inflammatory properties. In this study, we demonstrated that 15-keto-PGE(2) post-translationally modified the nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) subunits p105/p50 and p65 at Cys59 and Cys120 sites, respectively, hence...

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Detalles Bibliográficos
Autores principales: Hee, Siow-Wey, Chang, Yi-Cheng, Su, Lynn, Chen, Ing-Jung, Jeng, Yung-Ming, Hsieh, Meng-Lun, Chang, Yu-Chia, Li, Fu-An, Liao, Daniel, Chen, Shiau-Mei, Chuang, Lee-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10551900/
https://www.ncbi.nlm.nih.gov/pubmed/37810249
http://dx.doi.org/10.1016/j.isci.2023.107997