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Engineered small extracellular vesicle‑mediated NOX4 siRNA delivery for targeted therapy of cardiac hypertrophy

Small‐interfering RNA (siRNA) therapy is considered a powerful therapeutic strategy for treating cardiac hypertrophy, an important risk factor for subsequent cardiac morbidity and mortality. However, the lack of safe and efficient in vivo delivery of siRNAs is a major challenge for broadening its cl...

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Detalles Bibliográficos
Autores principales: Kang, Ji‐Young, Mun, Dasom, Chun, Yumin, Park, Da‐Seul, Kim, Hyoeun, Yun, Nuri, Joung, Boyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552075/
https://www.ncbi.nlm.nih.gov/pubmed/37795828
http://dx.doi.org/10.1002/jev2.12371