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B-cells and regulatory T-cells in the microenvironment of HER2+ breast cancer are associated with decreased survival: a real-world analysis of women with HER2+ metastatic breast cancer

BACKGROUND: Despite major improvements in treatment of HER2-positive metastatic breast cancer (MBC), only few patients achieve complete remission and remain progression free for a prolonged time. The tumor immune microenvironment plays an important role in the response to treatment in HER2-positive...

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Detalles Bibliográficos
Autores principales: Steenbruggen, Tessa G., Wolf, Denise M., Campbell, Michael J., Sanders, Joyce, Cornelissen, Sten, Thijssen, Bram, Salgado, Roberto A., Yau, Christina, O-Grady, Nick, Basu, Amrita, Bhaskaran, Rajith, Mittempergher, Lorenza, Hirst, Gillian L., Coppe, Jean-Philippe, Kok, Marleen, Sonke, Gabe S., van ‘t Veer, Laura J., Horlings, Hugo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552219/
https://www.ncbi.nlm.nih.gov/pubmed/37794508
http://dx.doi.org/10.1186/s13058-023-01717-1