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HycDemux: a hybrid unsupervised approach for accurate barcoded sample demultiplexing in nanopore sequencing
DNA barcodes enable Oxford Nanopore sequencing to sequence multiple barcoded DNA samples on a single flow cell. DNA sequences with the same barcode need to be grouped together through demultiplexing. As the number of samples increases, accurate demultiplexing becomes difficult. We introduce HycDemux...
Autores principales: | Han, Renmin, Qi, Junhai, Xue, Yang, Sun, Xiujuan, Zhang, Fa, Gao, Xin, Li, Guojun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552309/ https://www.ncbi.nlm.nih.gov/pubmed/37798751 http://dx.doi.org/10.1186/s13059-023-03053-1 |
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