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HycDemux: a hybrid unsupervised approach for accurate barcoded sample demultiplexing in nanopore sequencing

DNA barcodes enable Oxford Nanopore sequencing to sequence multiple barcoded DNA samples on a single flow cell. DNA sequences with the same barcode need to be grouped together through demultiplexing. As the number of samples increases, accurate demultiplexing becomes difficult. We introduce HycDemux...

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Detalles Bibliográficos
Autores principales: Han, Renmin, Qi, Junhai, Xue, Yang, Sun, Xiujuan, Zhang, Fa, Gao, Xin, Li, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552309/
https://www.ncbi.nlm.nih.gov/pubmed/37798751
http://dx.doi.org/10.1186/s13059-023-03053-1