Genotype-free demultiplexing of pooled single-cell RNA-seq

A variety of methods have been developed to demultiplex pooled samples in a single cell RNA sequencing (scRNA-seq) experiment which either require hashtag barcodes or sample genotypes prior to pooling. We introduce scSplit which utilizes genetic differences inferred from scRNA-seq data alone to demu...

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Detalles Bibliográficos
Autores principales: Xu, Jun, Falconer, Caitlin, Nguyen, Quan, Crawford, Joanna, McKinnon, Brett D., Mortlock, Sally, Senabouth, Anne, Andersen, Stacey, Chiu, Han Sheng, Jiang, Longda, Palpant, Nathan J., Yang, Jian, Mueller, Michael D., Hewitt, Alex W., Pébay, Alice, Montgomery, Grant W., Powell, Joseph E., Coin, Lachlan J.M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921391/
https://www.ncbi.nlm.nih.gov/pubmed/31856883
http://dx.doi.org/10.1186/s13059-019-1852-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921391/
https://www.ncbi.nlm.nih.gov/pubmed/31856883
http://dx.doi.org/10.1186/s13059-019-1852-7

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