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Preosteoclast plays a pathogenic role in syndesmophyte formation of ankylosing spondylitis through the secreted PDGFB — GRB2/ERK/RUNX2 pathway

OBJECTIVES: Ankylosing spondylitis (AS) is a chronic inflammatory disease that mainly affects the sacroiliac joint and spine. However, the real mechanisms of immune cells acting on syndesmophyte formation in AS are not well identified. We aimed to find the key AS-associated cytokine and assess its p...

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Detalles Bibliográficos
Autores principales: Tang, Yulong, Yang, Kai, Liu, Qingmei, Ma, Yanyun, Zhu, Hao, Tang, Kunhai, Geng, Chengchun, Xie, Jiangnan, Zhuo, Dachun, Wu, Wenyu, Jin, Li, Xiao, Wenze, Wang, Jiucun, Zhu, Qi, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552372/
https://www.ncbi.nlm.nih.gov/pubmed/37798786
http://dx.doi.org/10.1186/s13075-023-03142-3