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Metabolic Engineering of Escherichia coli for Efficient Production of Pseudouridine
[Image: see text] Pseudouridine-incorporated mRNA vaccines can enhance protein expression and reduce immunogenicity, leading to a high demand for pseudouridine to be used in mRNA drug production. To achieve the low-cost production of pseudouridine, Escherichia coli was systematically modified to uti...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552469/ https://www.ncbi.nlm.nih.gov/pubmed/37810737 http://dx.doi.org/10.1021/acsomega.3c05219 |