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Metabolic Engineering of Escherichia coli for Efficient Production of Pseudouridine

[Image: see text] Pseudouridine-incorporated mRNA vaccines can enhance protein expression and reduce immunogenicity, leading to a high demand for pseudouridine to be used in mRNA drug production. To achieve the low-cost production of pseudouridine, Escherichia coli was systematically modified to uti...

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Detalles Bibliográficos
Autores principales: Zhou, Min, Tang, Ruyu, Wei, Liyuan, Wang, Jidong, Qi, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552469/
https://www.ncbi.nlm.nih.gov/pubmed/37810737
http://dx.doi.org/10.1021/acsomega.3c05219