Cargando…
Backbone Conformational Equilibrium in Mismatched DNA Correlates with Enzyme Activity
[Image: see text] T:G mismatches in mammals arise primarily from the deamination of methylated CpG sites or the incorporation of improper nucleotides. The process by which repair enzymes such as thymine DNA glycosylase (TDG) identify a canonical DNA base in the incorrect pairing context remains a my...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552547/ https://www.ncbi.nlm.nih.gov/pubmed/37699121 http://dx.doi.org/10.1021/acs.biochem.3c00230 |