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Backbone Conformational Equilibrium in Mismatched DNA Correlates with Enzyme Activity

[Image: see text] T:G mismatches in mammals arise primarily from the deamination of methylated CpG sites or the incorporation of improper nucleotides. The process by which repair enzymes such as thymine DNA glycosylase (TDG) identify a canonical DNA base in the incorrect pairing context remains a my...

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Detalles Bibliográficos
Autores principales:	Westwood, M. N., Pilarski, A., Johnson, C., Mamoud, S., Meints, G. A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552547/ https://www.ncbi.nlm.nih.gov/pubmed/37699121 http://dx.doi.org/10.1021/acs.biochem.3c00230

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