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Periostin C-Terminal Is Intrinsically Disordered and Interacts with 143 Proteins in an In Vitro Epidermal Model of Atopic Dermatitis

[Image: see text] Human periostin is a 78–91 kDa matricellular protein implicated in extracellular matrix remodeling, tumor development, metastasis, and inflammatory diseases like atopic dermatitis, psoriasis, and asthma. The protein consists of six domains, including an N-terminal Cys-rich CROPT do...

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Detalles Bibliográficos
Autores principales: Rusbjerg-Weberskov, Christian E., Johansen, Mette Liere, Nowak, Jan S., Otzen, Daniel E., Pedersen, Jan Skov, Enghild, Jan J., Nielsen, Nadia Sukusu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552548/
https://www.ncbi.nlm.nih.gov/pubmed/37704583
http://dx.doi.org/10.1021/acs.biochem.3c00176