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Metal Binding of Alzheimer’s Amyloid-β and Its Effect on Peptide Self-Assembly

[Image: see text] Metal ions have been identified as key factors modulating the aggregation of amyloid-β peptide (Aβ) implicated in Alzheimer’s disease (AD). The presence of elevated levels of metal ions in the amyloid plaques in AD patients supports the notion that the dysfunction of metal homeosta...

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Detalles Bibliográficos
Autor principal: Abelein, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552549/
https://www.ncbi.nlm.nih.gov/pubmed/37733746
http://dx.doi.org/10.1021/acs.accounts.3c00370