Directly reprogrammed fragile X syndrome dorsal forebrain precursor cells generate cortical neurons exhibiting impaired neuronal maturation

INTRODUCTION: The neurodevelopmental disorder fragile X syndrome (FXS) is the most common monogenic cause of intellectual disability associated with autism spectrum disorder. Inaccessibility to developing human brain cells is a major barrier to studying FXS. Direct-to-neural precursor reprogramming...

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Detalles Bibliográficos
Autores principales: Edwards, Nicole, Combrinck, Catharina, McCaughey-Chapman, Amy, Connor, Bronwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552551/
https://www.ncbi.nlm.nih.gov/pubmed/37810261
http://dx.doi.org/10.3389/fncel.2023.1254412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552551/
https://www.ncbi.nlm.nih.gov/pubmed/37810261
http://dx.doi.org/10.3389/fncel.2023.1254412

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