Activated KRAS reprograms neural progenitor cells to glioma stem cell-like phenotype

Glioma is the most common primary brain tumor. Glioma stem cells (GSCs) are the origin of gliomagenesis and may develop from normal neural progenitor cells (NPCs). However, how neoplastic transformation occurs in normal NPCs and the role of the Ras/Raf/MAPK pathway in NPC transformation is unclear....

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Detalles Bibliográficos
Autores principales: Qin, Zixi, Liang, Weiye, Zhang, Zixuan, Li, Peiwen, Wang, Tianyu, Chen, Qianyu, Guo, Baoyin, Zhong, Ying, Kang, Hui, Wang, Lihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552691/
https://www.ncbi.nlm.nih.gov/pubmed/37326110
http://dx.doi.org/10.3892/ijo.2023.5536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552691/
https://www.ncbi.nlm.nih.gov/pubmed/37326110
http://dx.doi.org/10.3892/ijo.2023.5536

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