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NQO1 drives glioblastoma cell aggressiveness through EMT induction via the PI3K/Akt/mTOR/Snail pathway

Glioblastoma multiforme (GBM) is the most frequent and lethal cancer derived from the central nervous system, of which the mesenchymal (MES) subtype seriously influences the survival and prognosis of patients. NAD(P)H: quinone acceptor oxidoreductase 1 (NQO1) serves an important role in the carcinog...

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Detalles Bibliográficos
Autores principales: Zheng, Lan, Yang, Shipeng, Xu, Ran, Yang, Yang, Quan, Jishu, Lin, Zhenhua, Quan, Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552716/
https://www.ncbi.nlm.nih.gov/pubmed/37594082
http://dx.doi.org/10.3892/ijo.2023.5558