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Ebselen oxide and derivatives are new allosteric HER2 inhibitors for HER2‐positive cancers
Human epidermal growth factor receptor 2 (ErbB2/HER2) is a tyrosine kinase receptor that is overexpressed in 25% of primary human breast cancers, as well as in multiple other cancers. HER2‐targeted therapies improved progression‐free and overall survival in patients with HER2(+) breast cancers. Howe...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552892/ https://www.ncbi.nlm.nih.gov/pubmed/36912768 http://dx.doi.org/10.1002/1878-0261.13419 |