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Promyelocytic leukemia protein regulates angiogenesis and epithelial–mesenchymal transition to limit metastasis in MDA‐MB‐231 breast cancer cells

Promyelocytic leukemia protein (PML) modulates diverse cell functions that contribute to both tumor suppressor and pro‐oncogenic effects, depending on the cellular context. We show here that PML knockdown (KD) in MDA‐MB‐231, but not MCF7, breast cancer cells, prolonged stem‐cell‐like survival, and i...

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Detalles Bibliográficos
Autores principales: Vogiatzoglou, Amalia P., Spanou, Syrago, Sachini, Nikoleta, Drakos, Elias, Nikolaou, Christoforos, Makatounakis, Takis, Kretsovali, Androniki, Papamatheakis, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552902/
https://www.ncbi.nlm.nih.gov/pubmed/37518985
http://dx.doi.org/10.1002/1878-0261.13501