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Brain-wide genome-wide colocalization study for integrating genetics, transcriptomics and brain morphometry in Alzheimer’s disease

Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases. However, the AD mechanism has not yet been fully elucidated to date, hindering the development of effective therapies. In our work, we perform a brain imaging genomics study to link genetics, single-cell gene expression d...

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Detalles Bibliográficos
Autores principales: Bao, Jingxuan, Wen, Junhao, Wen, Zixuan, Yang, Shu, Cui, Yuhan, Yang, Zhijian, Erus, Guray, Saykin, Andrew J., Long, Qi, Davatzikos, Christos, Shen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10552907/
https://www.ncbi.nlm.nih.gov/pubmed/37634885
http://dx.doi.org/10.1016/j.neuroimage.2023.120346