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Structure, dynamics and free energy studies on the effect of point mutations on SARS-CoV-2 spike protein binding with ACE2 receptor

The ongoing COVID-19 pandemic continues to infect people worldwide, and the virus continues to evolve in significant ways which can pose challenges to the efficiency of available vaccines and therapeutic drugs and cause future pandemic. Therefore, it is important to investigate the binding and inter...

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Detalles Bibliográficos
Autores principales: Rucker, George, Qin, Hong, Zhang, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553274/
https://www.ncbi.nlm.nih.gov/pubmed/37796794
http://dx.doi.org/10.1371/journal.pone.0289432