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Significant decrease of maternal mitochondria carryover using optimized spindle-chromosomal complex transfer

Mutations in mitochondrial DNA (mtDNA) contribute to a variety of serious multi-organ human diseases, which are strictly inherited from the maternal germline. However, there is currently no curative treatment. Attention has been focused on preventing the transmission of mitochondrial diseases throug...

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Detalles Bibliográficos
Autores principales: Liao, Xiaoyu, Li, Wenzhi, Lin, Kaibo, Jin, Wei, Zhang, Shaozhen, Wang, Yao, Ma, Meng, Xie, Yating, Yu, Weina, Yan, Zhiguang, Gao, Hongyuan, Zhao, Leiwen, Si, Jiqiang, Wang, Yun, Lin, Jiaying, Chen, Chen, Chen, Li, Kuang, Yanping, Lyu, Qifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553349/
https://www.ncbi.nlm.nih.gov/pubmed/37796762
http://dx.doi.org/10.1371/journal.pbio.3002313