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Significant decrease of maternal mitochondria carryover using optimized spindle-chromosomal complex transfer
Mutations in mitochondrial DNA (mtDNA) contribute to a variety of serious multi-organ human diseases, which are strictly inherited from the maternal germline. However, there is currently no curative treatment. Attention has been focused on preventing the transmission of mitochondrial diseases throug...
Autores principales: | Liao, Xiaoyu, Li, Wenzhi, Lin, Kaibo, Jin, Wei, Zhang, Shaozhen, Wang, Yao, Ma, Meng, Xie, Yating, Yu, Weina, Yan, Zhiguang, Gao, Hongyuan, Zhao, Leiwen, Si, Jiqiang, Wang, Yun, Lin, Jiaying, Chen, Chen, Chen, Li, Kuang, Yanping, Lyu, Qifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553349/ https://www.ncbi.nlm.nih.gov/pubmed/37796762 http://dx.doi.org/10.1371/journal.pbio.3002313 |
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