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Coarse-grained molecular dynamics-guided immunoinformatics to explain the binder and non-binder classification of Cytotoxic T-cell epitope for SARS-CoV-2 peptide-based vaccine discovery

Epitope-based peptide vaccine can elicit T-cell immunity against SARS-CoV-2 to clear the infection. However, finding the best epitope from the whole antigen is challenging. A peptide screening using immunoinformatics usually starts from MHC-binding peptide, immunogenicity, cross-reactivity with the...

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Detalles Bibliográficos
Autores principales: Yusuf, Muhammad, Destiarani, Wanda, Widayat, Wahyu, Yosua, Yosua, Gumilar, Gilang, Tanudireja, Angelica Shalfani, Rohmatulloh, Fauzian Giansyah, Maulana, Farhan Azhwin, Baroroh, Umi, Hardianto, Ari, Maharani, Rani, Nurainy, Neni, Wijayadikusumah, Acep Riza, Ristandi, Ryan B., Atmosukarto, Ines Irene Caterina, Subroto, Toto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553366/
https://www.ncbi.nlm.nih.gov/pubmed/37796941
http://dx.doi.org/10.1371/journal.pone.0292156