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Coarse-grained molecular dynamics-guided immunoinformatics to explain the binder and non-binder classification of Cytotoxic T-cell epitope for SARS-CoV-2 peptide-based vaccine discovery
Epitope-based peptide vaccine can elicit T-cell immunity against SARS-CoV-2 to clear the infection. However, finding the best epitope from the whole antigen is challenging. A peptide screening using immunoinformatics usually starts from MHC-binding peptide, immunogenicity, cross-reactivity with the...
Autores principales: | Yusuf, Muhammad, Destiarani, Wanda, Widayat, Wahyu, Yosua, Yosua, Gumilar, Gilang, Tanudireja, Angelica Shalfani, Rohmatulloh, Fauzian Giansyah, Maulana, Farhan Azhwin, Baroroh, Umi, Hardianto, Ari, Maharani, Rani, Nurainy, Neni, Wijayadikusumah, Acep Riza, Ristandi, Ryan B., Atmosukarto, Ines Irene Caterina, Subroto, Toto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553366/ https://www.ncbi.nlm.nih.gov/pubmed/37796941 http://dx.doi.org/10.1371/journal.pone.0292156 |
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