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Mouse methylation profiles for leukocyte cell types, and estimation of leukocyte fractions in inflamed gastrointestinal DNA samples

Precise analysis of tissue DNA and RNA samples is often hampered by contaminating non-target cells whose amounts are highly variable. DNA methylation profiles are specific to cell types, and can be utilized for assessment of the fraction of such contaminating non-target cells. Here, we aimed 1) to i...

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Detalles Bibliográficos
Autores principales: Nishiyama, Kazuhiro, Nishinakamura, Hitomi, Takeshima, Hideyuki, Yuyu, Liu, Takeuchi, Chihiro, Hattori, Naoko, Takeda, Haruna, Yamashita, Satoshi, Wakabayashi, Mika, Sato, Kotomi, Obama, Kazutaka, Ushijima, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553802/
https://www.ncbi.nlm.nih.gov/pubmed/37797047
http://dx.doi.org/10.1371/journal.pone.0290034