Key transcriptional effectors of the pancreatic acinar phenotype and oncogenic transformation

Proper maintenance of mature cellular phenotypes is essential for stable physiology, suppression of disease states, and resistance to oncogenic transformation. We describe the transcriptional regulatory roles of four key DNA-binding transcription factors (Ptf1a, Nr5a2, Foxa2 and Gata4) that sit at t...

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Detalles Bibliográficos
Autores principales: Azevedo-Pouly, Ana, Hale, Michael A., Swift, Galvin H., Hoang, Chinh Q., Deering, Tye G., Xue, Jumin, Wilkie, Thomas M., Murtaugh, L. Charles, MacDonald, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553828/
https://www.ncbi.nlm.nih.gov/pubmed/37796967
http://dx.doi.org/10.1371/journal.pone.0291512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553828/
https://www.ncbi.nlm.nih.gov/pubmed/37796967
http://dx.doi.org/10.1371/journal.pone.0291512

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