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Key transcriptional effectors of the pancreatic acinar phenotype and oncogenic transformation
Proper maintenance of mature cellular phenotypes is essential for stable physiology, suppression of disease states, and resistance to oncogenic transformation. We describe the transcriptional regulatory roles of four key DNA-binding transcription factors (Ptf1a, Nr5a2, Foxa2 and Gata4) that sit at t...
Autores principales: | Azevedo-Pouly, Ana, Hale, Michael A., Swift, Galvin H., Hoang, Chinh Q., Deering, Tye G., Xue, Jumin, Wilkie, Thomas M., Murtaugh, L. Charles, MacDonald, Raymond J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553828/ https://www.ncbi.nlm.nih.gov/pubmed/37796967 http://dx.doi.org/10.1371/journal.pone.0291512 |
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