SAT016 Small Compounds Modulate Glucocorticoid Receptor Function By Binding To A Novel Allosteric Pocket

Disclosure: A. Jimenez-Panizo: None. The glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that controls metabolic and homeostatic processes essential for life. This receptor exerts its functions by binding to corticosteroids through its ligand-binding domain (LBD), which...

Descripción completa

Detalles Bibliográficos
Autores principales: Jimenez-Panizo, Alba, Alegre, Andrea, Fuentes-Prior, Pablo, Hager, Gordon L, Estebanez-Perpina, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Steroid Hormones, Nuclear Receptors And Coregulators
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553996/
http://dx.doi.org/10.1210/jendso/bvad114.1754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10553996/
http://dx.doi.org/10.1210/jendso/bvad114.1754

Ejemplares similares