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OR20-05 Generation Of CDH23-mutated Pituitary Neuroendocrine Tumor Organoids From Induced Pluripotent Stem Cells To Model Cushing’s Disease Pathogenesis

Disclosure: J. Chakrabarti: None. S. Mallick: None. J. Churko: None. J. Eschbacher: None. A.S. Little: None. K.C. Yuen: None. Y. Zavros: None. Background: Cushing's disease (CD) is a debilitating disease caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary tumor (PitNET). While m...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Jayati, Mallick, Saptarshi, Churko, Jared, Eschbacher, Jennifer, Little, Andrew S, Ji Yuen, Kevin Choong, Zavros, Yana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10554281/
http://dx.doi.org/10.1210/jendso/bvad114.1314