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OR33-06 Pioneer Factor Foxa2 Mediates Chromatin Conformation Changes In Ligand-dependent Activation Of FXR

Disclosure: Y. Hao: None. L. Han: None. C. Wu: None. I. Bochkis: None. Activation of nuclear receptors, a family of ligand-dependent transcription factors, is used extensively in pharmacology to develop drug targets for diverse medical conditions, including metabolic disease and cancer. We have prev...

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Detalles Bibliográficos
Autores principales: Hao, Yi, Han, Lu, Wu, Carol, Bochkis, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10554588/
http://dx.doi.org/10.1210/jendso/bvad114.1774