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SAT090 Serum Ketone Levels Are Disproportionate To Beta-Oxidation In Insulin Receptor Mutation Compared Vs Lipodystrophy Patients

Disclosure: R. Klein: None. S.T. Chung: None. R.J. Brown: None. Introduction: Ketogenic substrates mainly derive from fatty acid (FA) metabolism via hepatic β-oxidation (βOx). βOx catabolizes FAs to acetyl-CoA, which can make ATP via the TCA cycle or ketones. Ketones are cleared peripherally by mono...

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Detalles Bibliográficos
Autores principales: Klein, Rachael, Chung, Stephanie T, Brown, Rebecca J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10554747/
http://dx.doi.org/10.1210/jendso/bvad114.956