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SAT074 Induction Of Insulin Hypersecretion Uncovers Distinctions Between Adaptive And Maladaptive Endoplasmic Reticulum Stress Response In Beta Cells

Disclosure: G. Roy: None. K. Rodrigues dos Santos: None. M.B. Kwakye: None. Z. Tan: None. T.S. Johnson: None. M.A. Kalwat: None. Pancreatic islet β-cells release insulin to maintain glucose homeostasis. β-cells must translate, package, and secrete large amounts of insulin. During this process the un...

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Detalles Bibliográficos
Autores principales: Roy, Gitanjali, dos Santos, Karina Rodrigues, Kwakye, Michael B, Tan, Zhiyong, Johnson, Travis S, Kalwat, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555094/
http://dx.doi.org/10.1210/jendso/bvad114.941