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HER3/Akt/mTOR pathway is a key therapeutic target for the reduction of triple-negative breast cancer metastasis via the inhibition of CXCR4 expression

Triple-negative breast cancer (TNBC), a highly metastatic subtype of breast cancer, and it has the worst prognosis among all subtypes of breast cancer. However, no effective systematic therapy is currently available for TNBC metastasis. Therefore, novel therapies targeting the key molecular mechanis...

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Detalles Bibliográficos
Autores principales: Takeda, Tomoya, Tsubaki, Masanobu, Genno, Shuji, Tokunaga, Kenta, Tanaka, Remi, Nishida, Shozo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555474/
https://www.ncbi.nlm.nih.gov/pubmed/37477145
http://dx.doi.org/10.3892/ijmm.2023.5283