CycloZ Improves Hyperglycemia and Lipid Metabolism by Modulating Lysine Acetylation in KK-Ay Mice

BACKGROUND: CycloZ, a combination of cyclo-His-Pro and zinc, has anti-diabetic activity. However, its exact mode of action remains to be elucidated. METHODS: KK-Ay mice, a type 2 diabetes mellitus (T2DM) model, were administered CycloZ either as a preventive intervention, or as a therapy. Glycemic c...

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Detalles Bibliográficos
Autores principales: Jeon, Jongsu, Lee, Dohyun, Kim, Bobae, Park, Bo-Yoon, Oh, Chang Joo, Kim, Min-Ji, Jeon, Jae-Han, Lee, In-Kyu, Park, Onyu, Baek, Seoyeong, Lim, Chae Won, Ryu, Dongryeol, Fang, Sungsoon, Auwerx, Johan, Kim, Kyong-Tai, Jung, Hoe-Yune
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Diabetes Association 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555534/
https://www.ncbi.nlm.nih.gov/pubmed/37098411
http://dx.doi.org/10.4093/dmj.2022.0244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555534/
https://www.ncbi.nlm.nih.gov/pubmed/37098411
http://dx.doi.org/10.4093/dmj.2022.0244

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