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Polyploidy, EZH2 upregulation, and transformation in cytomegalovirus-infected human ovarian epithelial cells

Human cytomegalovirus (HCMV) infection has been implicated in epithelial ovarian cancer (OC). Polyploidy giant cancer cells (PGCCs) have been observed in high-grade serous ovarian carcinoma (HGSOC); they possess cancer stem cell-like characteristics and give rise to progeny cells expressing epitheli...

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Detalles Bibliográficos
Autores principales: El Baba, Ranim, Haidar Ahmad, Sandy, Monnien, Franck, Mansar, Racha, Bibeau, Frédéric, Herbein, Georges
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555822/
https://www.ncbi.nlm.nih.gov/pubmed/37634008
http://dx.doi.org/10.1038/s41388-023-02813-4