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Spatiotemporal, optogenetic control of gene expression in organoids
Organoids derived from stem cells have become an increasingly important tool for studying human development and modeling disease. However, methods are still needed to control and study spatiotemporal patterns of gene expression in organoids. Here we combined optogenetics and gene perturbation techno...
Autores principales: | Legnini, Ivano, Emmenegger, Lisa, Zappulo, Alessandra, Rybak-Wolf, Agnieszka, Wurmus, Ricardo, Martinez, Anna Oliveras, Jara, Cledi Cerda, Boltengagen, Anastasiya, Hessler, Talé, Mastrobuoni, Guido, Kempa, Stefan, Zinzen, Robert, Woehler, Andrew, Rajewsky, Nikolaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555836/ https://www.ncbi.nlm.nih.gov/pubmed/37735569 http://dx.doi.org/10.1038/s41592-023-01986-w |
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