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Waning of antibody levels induced by a 13-valent pneumococcal conjugate vaccine, using a 3 + 0 schedule, within the first year of life among children younger than 5 years in Blantyre, Malawi: an observational, population-level, serosurveillance study

BACKGROUND: Pneumococcal conjugate vaccines (PCVs) induce serotype-specific IgG antibodies, effectively reducing vaccine-serotype carriage and invasive pneumococcal disease (IPD). IgG production wanes approximately 1 month after vaccination in absence of serotype-specific exposure. With uncertainty...

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Detalles Bibliográficos
Autores principales: Swarthout, Todd D, Henrion, Marc Y R, Thindwa, Deus, Meiring, James E, Mbewe, Maurice, Kalizang’Oma, Akuzike, Brown, Comfort, Msefula, Jacquline, Moyo, Brewster, Mataya, Andrew A, Barnaba, Susanne, Pearce, Emma, Gordon, Melita, Goldblatt, David, French, Neil, Heyderman, Robert S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science ;, The Lancet Pub. Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555849/
https://www.ncbi.nlm.nih.gov/pubmed/36029796
http://dx.doi.org/10.1016/S1473-3099(22)00438-8