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Targeting Desulfovibrio vulgaris flagellin-induced NAIP/NLRC4 inflammasome activation in macrophages attenuates ulcerative colitis

INTRODUCTION: The perturbations of gut microbiota could interact with excessively activated immune responses and play key roles in the etiopathogenesis of ulcerative colitis (UC). Desulfovibrio, the most predominant sulfate reducing bacteria (SRB) resided in the human gut, was observed to overgrow i...

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Detalles Bibliográficos
Autores principales: An, Yaping, Zhai, Zihan, Wang, Xin, Ding, Yiyun, He, Linlin, Li, Lingfeng, Mo, Qi, Mu, Chenlu, Xie, Runxiang, Liu, Tianyu, Zhong, Weilong, Wang, Bangmao, Cao, Hailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555950/
https://www.ncbi.nlm.nih.gov/pubmed/37586642
http://dx.doi.org/10.1016/j.jare.2023.08.008