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Metabolic profiling to evaluate the impact of amantadine and rimantadine on the secondary metabolism of a model organism
Metabolic profiling offers huge potential to highlight markers and mechanisms in support of toxicology and pathology investigations during drug development. The main objective was to modify therapy with adamantane derivatives: amantadine and rimantadine, to increase their bioavailability and evaluat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555991/ https://www.ncbi.nlm.nih.gov/pubmed/37798340 http://dx.doi.org/10.1038/s41598-023-43540-w |