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Macrophage depletion attenuates degeneration of spiral ganglion neurons in kanamycin-induced unilateral hearing loss model

Pathological conditions in cochlea, such as ototoxicity, acoustic trauma, and age-related cochlear degeneration, induce cell death in the organ of Corti and degeneration of the spiral ganglion neurons (SGNs). Although macrophages play an essential role after cochlear injury, its role in the SGNs is...

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Detalles Bibliográficos
Autores principales: Shimada, Mari Dias, Noda, Masao, Koshu, Ryota, Takaso, Yuji, Sugimoto, Hisashi, Ito, Makoto, Yoshizaki, Tomokazu, Hori, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555992/
https://www.ncbi.nlm.nih.gov/pubmed/37798459
http://dx.doi.org/10.1038/s41598-023-43927-9