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Macrophage depletion attenuates degeneration of spiral ganglion neurons in kanamycin-induced unilateral hearing loss model
Pathological conditions in cochlea, such as ototoxicity, acoustic trauma, and age-related cochlear degeneration, induce cell death in the organ of Corti and degeneration of the spiral ganglion neurons (SGNs). Although macrophages play an essential role after cochlear injury, its role in the SGNs is...
Autores principales: | Shimada, Mari Dias, Noda, Masao, Koshu, Ryota, Takaso, Yuji, Sugimoto, Hisashi, Ito, Makoto, Yoshizaki, Tomokazu, Hori, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555992/ https://www.ncbi.nlm.nih.gov/pubmed/37798459 http://dx.doi.org/10.1038/s41598-023-43927-9 |
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