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ClpP/ClpX deficiency impairs mitochondrial functions and mTORC1 signaling during spermatogenesis
Caseinolytic protease proteolytic subunit (ClpP) and caseinolytic protease X (ClpX) are mitochondrial matrix peptidases that activate mitochondrial unfolded protein response to maintain protein homeostasis in the mitochondria. However, the role of ClpP and ClpX in spermatogenesis remains largely unk...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556007/ https://www.ncbi.nlm.nih.gov/pubmed/37798322 http://dx.doi.org/10.1038/s42003-023-05372-2 |