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ClpP/ClpX deficiency impairs mitochondrial functions and mTORC1 signaling during spermatogenesis

Caseinolytic protease proteolytic subunit (ClpP) and caseinolytic protease X (ClpX) are mitochondrial matrix peptidases that activate mitochondrial unfolded protein response to maintain protein homeostasis in the mitochondria. However, the role of ClpP and ClpX in spermatogenesis remains largely unk...

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Detalles Bibliográficos
Autores principales: Guo, Chenxi, Xiao, Yuan, Gu, Jingkai, Zhao, Peikun, Hu, Zhe, Zheng, Jiahuan, Hua, Renwu, Hai, Zhuo, Su, Jiaping, Zhang, Jian V., Yeung, William S. B., Wang, Tianren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556007/
https://www.ncbi.nlm.nih.gov/pubmed/37798322
http://dx.doi.org/10.1038/s42003-023-05372-2

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