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Increasing dopamine synthesis in nigrostriatal circuits increases phasic dopamine release and alters dorsal striatal connectivity: implications for schizophrenia

One of the most robust neurochemical abnormalities reported in patients with schizophrenia is an increase in dopamine (DA) synthesis and release, restricted to the dorsal striatum (DS). This hyper functionality is strongly associated with psychotic symptoms and progresses in those who later transiti...

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Detalles Bibliográficos
Autores principales: Srivastav, Sunil, Cui, Xiaoying, Varela, Roger Bitencourt, Kesby, James P., Eyles, Darryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556015/
https://www.ncbi.nlm.nih.gov/pubmed/37798312
http://dx.doi.org/10.1038/s41537-023-00397-2