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Alum and a TLR7 agonist combined with built-in TLR4 and 5 agonists synergistically enhance immune responses against HPV RG1 epitope

To relieve the limitations of the human papillomavirus (HPV) vaccines based on L1 capsid protein, vaccine formulations based on RG1 epitope of HPV L2 using various built-in adjuvants are under study. Herein, we describe design and construction of a rejoined peptide (RP) harboring HPV16 RG1 epitope f...

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Detalles Bibliográficos
Autores principales: Mashhadi Abolghasem Shirazi, Maryam, Sadat, Seyed Mehdi, Haghighat, Setareh, Roohvand, Farzin, Arashkia, Arash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10556035/
https://www.ncbi.nlm.nih.gov/pubmed/37798448
http://dx.doi.org/10.1038/s41598-023-43965-3